Preview

Title in english

Advanced search

Frequency of hypertrophy development in the right ventricle with arterial hypertension according to post-mortem examination data

https://doi.org/10.34680/2076-8052.2024.4(138).542-551

Abstract

We have analyzed 674 autopsy reports of patients who died suddenly within 24 hours (myocardial infarction, stroke) and who suffered from arterial hypertension (AH) during their lifetime. There were 388 men (60,3%) and 255 women (39,7%). The study excluded cases that could have been caused by another cause of development (left ventricular hypertrophy, right ventricular hypertrophy) of LVH or RVH (defects, chronic obstructive pulmonary disease, etc.). The subjects were divided into 7 age groups, with a 10-year step, starting with the age category up to 29 years old and ending with the older age group of 80 years and older. Heart size was determined with a measuring metal ruler. Ventricular muscle thickness was determined on transverse incisions made midway between the apex of the heart and the valve ring. The normal thickness of the left ventricle wall (excluding papillary muscles) was taken to be 0,7-1,2 cm, and the right ventricle wall thickness was 0,2-0,3 cm. The authors concluded that right ventricular hypertrophy is a common manifestation of hypertension; there are gender differences in the incidence and severity of RVH. A close relationship was found between the hypertrophies of both ventricles of the heart. In the presence of LV hypertrophy, RV hypertrophy develops in a significant number of cases (87%).

About the Authors

V. R. Veber
Yaroslav-the-Wise Novgorod State University
Russian Federation

Veliky Novgorod



A. S. Kerimkulova
Astana Medical University
Kazakhstan

Nur-Sultan



S. V. Zhmailova
Yaroslav-the-Wise Novgorod State University
Russian Federation

Veliky Novgorod



L. G. Proshina
Yaroslav-the-Wise Novgorod State University
Russian Federation

Veliky Novgorod



E. E. Rumyantsev
Yaroslav-the-Wise Novgorod State University
Russian Federation

Veliky Novgorod



I. A. Ataev
Yaroslav-the-Wise Novgorod State University
Russian Federation

Veliky Novgorod



References

1. Laurel B. H., Carabello B.A. Hypertrophy of the left ventricle // Blood circulation. 2000. 102 (4). 470-479. DOI: 10.1161/01.cir.102.4.470

2. Basso C., Michaud K., d'Amati G. Banner J., Lucena J., Cunningham K., Leone O., Vink A., van der Wal A.C., Sheppard M. N. Hypertrophy of the heart during autopsy // Arch. Virchova. 2021. 479 (1). 79-94. DOI: 10.1007/s00428-021-03038-0

3. Fomin I. V. Khronicheskaya serdechnaya nedostatochnost' v Rossiyskoy Federatsii: chto segodnya my znayem i chto dolzhny delat' [Chronic heart failure in Russian federation: what do we know and what to do] // Russian Journal of Cardiology. 2016. 8 (136). 7-13. DOI: 10.15829/1560-4071-2016-8-7-13

4. Messerli F. H., Rimoldi S. F., Bangalore S. The Transition From Hypertension to Heart Failure: Contemporary Update // JACC Heart Failure. 2017. 5 (8). 543-551. DOI: 10.1016/j.jchf.2017.04.012

5. Tumuklu M. M., Erkorkmaz U., Ocal A. The impact of hypertension and hypertension-related left ventricle hypertrophy on right ventricle function. Echocardiography. 2007. 24 (4). 374-384. DOI: 10.1111/j.1540-8175.2007.00419.x

6. Cicala S., Galderisi M., Caso P., Petrocelli A., D'Errico A., de Divitiis O., Calabrò R. Right ventricular diastolic dysfunction in arterial systemic hypertension: analysis by pulsed tissue Doppler // European Journal of Echocardiography. 2002. 3 (2). 135-142. DOI: 10.1053/euje.2001.0124

7. Tadic M. Cuspidi C., Pencic B., Jozika L., Celic V. Relationship between right ventricular remodeling and heart rate variability in arterial hypertension // Journal of Hypertension. 2015. 33 (5). 1090-1097. DOI: 10.1097/HJH.0000000000000511

8. Perveen R., Hoque M. N., Ahmed K., Ahmed C. M., Jalil B. A., Parvin T., Osmany D. F., Rashid S., Rashid M. B., Nahar S., Shakil S. S. An Echocardiographic Study of the Right Ventricular Diastolic Function in Systemic Hypertension and Its Relation with the Left Ventricular Homologous Changes // Mymensingh Medical Journal. 2018. 27 (3). 596-602.

9. Nunez B. D., Messerli F. H., Amodeo C., Garavaglia G. E., Schmieder R. E., Frohlich E. D. Biventricular cardiac hypertrophy in essential hypertension // American Heart Journal. 1987. 114 (4-1). 813-818. DOI: 10.1016/0002-8703(87)90792-7

10. Cuspidi C., Sampieri L., Angioni L., Boselli L., Bragato R., Leonetti G., Zanchetti A. Right ventricular wall thickness and function in hypertensive patients with and without left ventricular hypertrophy: echo-Doppler study // Journal Hypertension. Suppl: official journal of the International society of Hypertension. 1989. 7 (6). S108-S109. DOI: 10.1097/00004872-198900076-00050

11. Kosiński A. Piwko G. M, Kamiński R., Nowicka E., Kaczyńska A., Zajączkowski M., Czerwiec K., Gleinert-Rożek M., Karnecki K., Gos T. Arterial hypertension and remodelling of the right ventricle // Folia Morphologica. 2022. 81 (2). 336-342. DOI: 10.5603/FM.a2021

12. Frolov V. A., Drozdova G. A., Rieger P., Blagonravov M. P. Nachal'nyye mekhanizmy formirovaniya «gipertonicheskogo serdtsa» [The initial mechanisms of the formation of a "hypertensive heart"] // Bulletin of Experimental Biology and Medicine. 2004. 137 (3). 249-252.

13. Korneva V. A., Petrovsky V. I., Dudanov I. P. Geometriya miokarda levogo zheludochka pri arterial'noy gipertonii na fone stenoziruyushchego tserebral'nogo ateroskleroza [Left ventricular myocardial geometry in arterial hypertension in patients with stenosing cerebral atherosclerosis] // Clinical Medicine. 2006. 3. 28-31.

14. Pedrinelli R., Canale M. L., Giannini C., Talini E., Dell'Omo G., Di Bello V. Abnormal right ventricular mechanics in early systemic hypertension: a two-dimensional strain imaging study // Europen Journal of Echocardiography. 2010. 11 (9). 738-742. DOI: 10.1093/ejechocard/jeq059

15. Cuspidi C., Negri F., Giudici V., Valerio C., Meani S., Sala C., Esposito A., Masaidi M., Zanchetti A., Mancia G. Prevalence and clinical correlates of right ventricular hypertrophy in essential hypertension // Journal of Hypertension. 2009. 27 (4). 854-860. DOI: 10.1097/HJH.0b013e328324eda0

16. Mandong B. M., Manasseh A. N., Ugwu B. T. Medicolegal autopsies in North Central Nigeria // East African Medical Journal. 2006. 83 (11). 626-630. DOI: 10.4314/eamj.v83i11.9480

17. Akhiwu W. O., Igbe A. P. Deaths with medicolegal implications in the elderly: experience from Benin City, Nigeria // Asian Journal of Gerontology and Geriatrics. 2011. 6. 35-37.

18. Abrikosov A. I. Osnovy chastnoy patologicheskoy anatomii [Fundamentals of private pathological anatomy]: textbook // Moscow: Medgiz, 1950. 472 р.

19. Khazanov A. T., Khazanov A. T., Chalisov I. A. Rukovodstvo po sektsionnomu kursu [Guide to the sectional course]. 3rd revised and enlarged edition. Moscow: Medicine, 1984. 176 р.

20. Avtandilov G. G. Meditsinskaya morfometriya [Medical morphometry]. Manual. Moscow: Medicine, 1990. 384 p.

21. Ji H., Niiranen T. J., Rader F., Henglin M., Kim A., Ebinger J.E., Claggett B., Merz C. N. B., Cheng S. Sex differences in blood pressure associations with cardiovascular outcomes // Circulation. 2021. 143 (7). 761-763. DOI: 10.1161/CIRCULATIONAHA.120.049360


Review

For citations:


Veber V.R., Kerimkulova A.S., Zhmailova S.V., Proshina L.G., Rumyantsev E.E., Ataev I.A. Frequency of hypertrophy development in the right ventricle with arterial hypertension according to post-mortem examination data. Title in english. 2024;(4(138)):542-551. (In Russ.) https://doi.org/10.34680/2076-8052.2024.4(138).542-551

Views: 19


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2076-8052 (Print)