Morphological manifestations of lung pathology in postcovid syndrome according to the results of autopsies for the period 2021-2023

Abstract

The problem of postcovid syndrome is relevant due to the high incidence of COVID-19, as well as the lack of awareness of medical professionals about its consequences, the pathogenesis of postcovid syndrome remains controversial and requires further research. The aim of the study was to determine the morphological manifestations of lung pathology in postcovid syndrome in 2021-2023 based on the study of autopsy material. After analyzing retrospective morphological studies of 34 autopsy cases diagnosed with postcovid syndrome, it was revealed that among the changes in lung tissue, chronic obstructive pulmonary disease (71%), common interstitial pneumonia (44%), bronchopneumonia (26%) and nonspecific interstitial pneumonia (24%) were the predominant processes. Hemorrhagic heart attacks also attracted attention (9%). Hypersensitivity pneumonitis, sarcoidosis and adenocarcinoma were more rare (3% each). It is worth noting that in almost all cases, there were phenomena of vasculitis, fullness and thrombosis of small vessels in the surrounding lung tissue.