Pathophysiological mechanisms of symptoms development in Kawasaki disease
https://doi.org/10.34680/2076-8052.2024.2(136).221-229
Abstract
Kawasaki disease is an acute inflammatory disease that typically affects medium- to small-sized muscular arteries, especially the coronary vessels. In Novgorod region, from 2016 to 2023, Kawasaki disease was diagnosed in 5 children aged 3 months to 12 years. All children were admitted to the hospital with fever lasting from 5 to 8 days. Complete blood count and urinalysis were performed. Levels of transaminases, C-reactive protein, total protein, albumin, glucose, and coagulation tests were done in the serum. Samples of blood cultures for sterility were taken. The research plan included such instrumental methods as electrocardiography, echocardiography, chest radiography, ultrasound examination of the abdominal cavity and kidneys. 3 patients were diagnosed Kawasaki disease before the 10th day of illness. A 3-month-old baby was diagnosed Kawasaki disease on the 13th day. Another baby of the same age was diagnosed posthumously. The pathogenetic mechanisms of detected symptoms in children were considered.
About the Authors
T. I. Okonenko
Yaroslav-the-Wise Novgorod State University
Russian Federation
Russian Federation
Veliky Novgorod
K. I. Mosicheva
Yaroslav-the-Wise Novgorod State University
Russian Federation
Russian Federation
Veliky Novgorod
Ye. Ye. Rumyantsev
Yaroslav-the-Wise Novgorod State University
Russian Federation
Russian Federation
Veliky Novgorod
I. A. Strikanov
Yaroslav-the-Wise Novgorod State University
Russian Federation
Russian Federation
Veliky Novgorod
F. R. Kurbonaliev
Yaroslav-the-Wise Novgorod State University
Russian Federation
Russian Federation
Veliky Novgorod
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Review
For citations:
Okonenko T.I., Mosicheva K.I., Rumyantsev Ye.Ye., Strikanov I.A., Kurbonaliev F.R. Pathophysiological mechanisms of symptoms development in Kawasaki disease. Title in english. 2024;(2(136)):221-229. (In Russ.) https://doi.org/10.34680/2076-8052.2024.2(136).221-229
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