Preview

Title in english

Advanced search

First cases of coagulation disorders as complications after the Gam-COVID-Vac (Sputnik V) vaccine

https://doi.org/10.34680/2076-8052.2021.3(124).61-64

Abstract

In the context of large-scale vaccination against the new coronavirus infection COVID-19, the study of possible complications after the introduction of the vaccine is of practical importance. To date, three vaccines against COVID-19 have been registered in the Russian Federation. The aim of this study was to analyze the first cases of coagulation disorders first reported after the introduction of the Gam-COVID-Vac (Sputnik V) vaccine. Cases of coagulation disorders that occurred in people of different ages, as well as changes in the biochemical blood test and general urine analysis, requiring additional research, were identified. An analogy is drawn with coagulogram disorders after vaccination against measles, rubella and mumps, and a hypothesis is proposed to explain the relationship of coagulation disorders with vaccination. The necessity and direction of further study are justified.

About the Authors

A. S. Denisenko
Новгородский государственный университет имени Ярослава Мудрого
Russian Federation


M. E. Riess
Новгородский государственный университет имени Ярослава Мудрого
Russian Federation


I. G. Kropachev
Центр общей врачебной (семейной) практики №3 поликлиники №4
Russian Federation


N. N. Nikitina
Новгородский государственный университет имени Ярослава Мудрого
Russian Federation


References

1. Munyer Th.P., Mangi R.J., Dolan Th., et al. Depressed Lymphocyte Function after Measles-Mumps-Rubella Vaccination. The Journal of Infectious Diseases, 1975, v.132, iss.1, pp.75-78.

2. Petrov V.Yu., Plakhuta T.G., Soskov G.I. Vaktsinoindutsirovannaya ostraya trombotsitopenicheskaya purpura u detey [Vaccine-induced acute thrombocytopenic purpura in children]. Pediatriya, 2006, no.6, pp.8-11.

3. Hamid A. Merchant CoViD vaccines and thrombotic events: EMA issued warning to patients and healthcare professionals. J of Pharm Policy and Pract., 2021, vol.14, article number: 32. DOI: doi.org/10.1186/s40545-021-00315-w

4. Anaev E.Kh., Knyazheskaya N.P. Koagulopatiya pri COVID19: fokus na antikoagulyantnuyu terapiyu [Coagulopathy in COVID-19: Focus on anticoagulant therapy]. Prakticheskaya pul'monologiya, 2020, no.1, pp.3-13.

5. Tang N., Li D., Wang X., et al. Abnormal Coagulation Parameters Are Associated with Poor Prognosis in Patients with Novel Coronavirus Pneumonia. J Thromb Haemost., 2020. DOI:10.1111/jth.14768


Review

For citations:


Denisenko A.S., Riess M.E., Kropachev I.G., Nikitina N.N. First cases of coagulation disorders as complications after the Gam-COVID-Vac (Sputnik V) vaccine. Title in english. 2021;(3(124)):61-64. (In Russ.) https://doi.org/10.34680/2076-8052.2021.3(124).61-64

Views: 62


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2076-8052 (Print)