Pathogenetic features of endogenous intoxication after uterine artery embolization in treatment of uterine fibrous

The analysis of the results of the study of endogenous intoxication after embolization of the uterine arteries (UAE) in 38 patients with the treatment of uterine fibroids was carried out. All women signed an informed consent to participate in the study and were familiarized with the purpose and design of the research. The indication for performing UAE was the presence of symptomatic uterine fibroids, regardless of the number and size of myomatous nodes. The criteria for the analysis were the features of the postoperative course and laboratory parameters characterizing endogenous intoxication in the postoperative period. The determination of endogenous intoxication was based on CASS / OA ratio, which reflects the ratio of quantitative indicators of nitrogen-containing compounds (ACC) and residual nitrogen (OA). In comparison with the results before UAE, a significant excess of residual nitrogen (P <0.05), nitrogen- containing compounds (P <0.05) and CASS / OA (P <0.05) indicators persists for more than 10 days. The results obtained indicated that, despite the lower trauma of UAE compared to laparoscopic conservative myomectomy, when choosing a method for treating uterine fibroids, it is necessary to take into account the risk of endogenous intoxication after UAE for a long time. It is advisable to continue research in this direction.

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