Viruses as an etiological and pathogenetic factor in the development of neurological and mental disorders using the example of Covid-19 and herpes virus infection (according to metaanalysis)
https://doi.org/10.34680/2076-8052.2022.4(129).42-45
Abstract
Currently, despite the gradual transition of a new coronavirus infection to a state of seasonal exacerbations, complications from COVID-19 still remain an urgent problem, especially those that affect the central nervous system. In this regard, studies aimed at distinguishing common for a group of acute respiratory viral infections and specific characteristics of COVID-19, including the development of post-COVID complications, namely mental and neurological disorders, are becoming increasingly relevant. The aim of this study was to determine the role of viruses (by the example of herpes viruses and the COVID-19 virus) as an etiological and pathogenetic factor in the development of mental and neurological disorders in different periods of the disease. Mental and neurological health disorders during the Covid period are characterized by clinically significant impairments in cognitive function, emotional regulation, or human behavior, accompanied by distress, as well as serious functional impairment.
About the Authors
N. E. MalyshevaRussian Federation
G. S. Arkhipov
Russian Federation
References
1. Doll J. R., Thompson R. L., Sawtell N. M. Infectious herpes simplex virus in the brain stem is correlated with reactivation in the trigeminal ganglia. J. Virol. 2019, vol.93(8), article no. e02209-18. doi: https://doi.org/10.1128/JVI.02209-18
2. Hasan M., Islam S., Chakraborty S., et al. Contriving a chimeric polyvalent vaccine to prevent infections caused by Herpes Simplex Virus (Type-1 and Type-2): an exploratory immunoinformatic approach. J. Biomol. Struct. Dyn., 2020, vol.38(10), pp.2898–2915. doi: https://doi.org/10.1080/07391102.2019.1647286
3. World Health Organization Website. Available at: https://www.who.int/ru (accessed: 21.09.2022).
4. Mahic M, Mjaaland S, Bovelstad HM, Gunnes N, Susser E, Bresnahan M, et al. Maternal Immunoreactivity to Herpes Simplex Virus 2 and Risk of Autism Spectrum Disorder in Male Offspring. MSphere, 2017, vol.2(1), article no. e00016-17. doi: https://doi.org/10.1128/mSphere.00016-17
5. Qiao H., Guo M., Shang J., et al. Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes. PLoS Pathog, 2020, vol.16(10), article no. e1008899. doi: https://doi.org/10.1371/journal.ppat.1008899
6. Bhupesh K. Prusty, Nitish Gulve, Sheila Govind, Gerhard R. F. Krueger, Julia Feichtinger, et al. Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders. Front Microbiol., 2018, vol.9, article no. 1955. doi: https://doi.org/10.3389/fmicb.2018.01955
7. Vremennyye metodicheskiye rekomendatsii «Profilaktika, diagnostika i lecheniye novoy koronavirusnoy infektsii (COVID-19)» [Temporary guidelines "Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)"]. Version 14 of 27.12.2021. Available at: http://nasci.ru/?id=68813&download=1 (accessed: 05.09.2022). (in Russian).
8. Abaturov A.E., Agafonova E.A., Krivusha E.L., Nikulina A.A. Patogenez COVID-19 [Pathogenesis of COVID-19]. Zdorov'ye rebenka — Child’s Health, 2020, vol.15, no.2, pp.133–134. doi: https://doi.org/10.22141/2224-0551.15.1.2020.200598
9. Postanovleniye pravitel'stva RF ot 31.01.2020 g. №66 «O vnesenii izmeneniya v perechen' zabolevaniy, predstavlyayushchikh opasnost' dlya okruzhayushchikh» [Decree of the Government of the Russian Federation of January 31, 2020, No.66 " On Amendments to the List of Diseases that Constitute a Danger to Others"]. (in Russian).
10. Baklaushev V.P., Kulemzin S.V., Gorchakov A.A., Lesnyak V.N., Yusubalieva G.M., Sotnikova A.G. COVID-19. Etiologiya, patogenez, diagnostika i lecheniye [COVID-19. Etiology, pathogenesis, diagnosis, and treatment]. Klinicheskaya praktika — Good Clinical Practice, 2020, vol.11(1), pp.7–20. doi: https://doi.org/10.17816/clinpract26339
11. de Paula J. J., Paiva R. E. R. P., Souza-Silva N. G., et al. Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings. Mol Psychiatry, 2022. doi: https://doi.org/10.1038/s41380-022-01632-5
12. Taquet M., Geddes J. R., Husain M. S., et al. Six-month neurological and psychiatric outcomes in 236,379 survivors of COVID-19. MedRxiv, 2021. doi: https://doi.org/10.1101/2021.01.16.21249950
Review
For citations:
Malysheva N.E., Arkhipov G.S. Viruses as an etiological and pathogenetic factor in the development of neurological and mental disorders using the example of Covid-19 and herpes virus infection (according to metaanalysis). Title in english. 2022;(4(129)):42-45. (In Russ.) https://doi.org/10.34680/2076-8052.2022.4(129).42-45