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Wilms tumor in a child at an early age: pathogenetic aspects, issues of timely diagnosis

https://doi.org/10.34680/2076-8052.2023.2(131).242-249

Abstract

The article deals with the issues of childhood oncopathology. Based on the literature data, the structure of oncological diseases in children in the Russian Federation and in the Novgorod region has been analyzed. It is shown that due to the rarity of oncological diseases in childhood, their detectability in outpatients in clinics requires active study with pediatricians by increasing staff awareness of this group of diseases and developing doctors’ oncological alertness skill in routine work. The article highlights the mechanisms of pathogenesis of a rare malignant embryonic neoplasm of the kidney — nephroblastoma (Wilms tumor), describes the clinical symptoms. The authors' own observation of an infant with a diagnosis of Wilms tumor is given. Conclusions were obtained about the course of the disease, the timing of the manifestation of the clinical picture. The observation demonstrates the relevance of timely screening ultrasound examination of the abdominal cavity and kidneys for children of the first year of life, the need to increase the level of knowledge in pediatric oncology of pediatricians of outpatient clinics, ultrasound diagnostics specialists, since timely diagnosis and early treatment significantly increase the likelihood of achieving remission of malignant diseases in children.

About the Authors

A. B. Ershevskaya
Yaroslaw-the-Wise Novgorod State University
Russian Federation

Ershevskaya A. B.,

Veliky Novgorod.



D. S. Isaeva
Yaroslaw-the-Wise Novgorod State University
Russian Federation

Isaeva D. S.,

Veliky Novgorod.



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For citations:


Ershevskaya A.B., Isaeva D.S. Wilms tumor in a child at an early age: pathogenetic aspects, issues of timely diagnosis. Title in english. 2023;(2(131)):242-249. (In Russ.) https://doi.org/10.34680/2076-8052.2023.2(131).242-249

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