vestnovsuВестник Новгородского государственного университетаVestnik of Novgorod State University2076-8052Новгородский государственный университет имени Ярослава Мудрого10.34680/2076-8052.2022.1(126).32-33vestnovsu-47Research ArticleКлиническая иммунология. Аллергология. Инфекционные болезниClinical immunology and infectious diseases. AllergologyОсобенности течения COVID-19 у медицинского персонала и больных гематологического стационараFeatures of the course of COVID-19 in medical personnel and hematology hospital patientsКулешоваА. В.KuleshovaA. V.

Санкт-Петербург

alenabs@yandex.ruЧеботкевичВ. Н.ChebotkevichV. N.

Санкт-Петербург

Российский научно-исследовательский институт гематологии и трансфузиологии Федерального медико-биологического агентстваRussian Federation20221909202301(126)3233Copyright © Кулешова А.В., Чеботкевич В.Н., 20232023Кулешова А.В., Чеботкевич В.Н.Kuleshova A.V., Chebotkevich V.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vestnovsu.elpub.ru/jour/article/view/47

Исследовали течение COVID-19 у 17 больных с различными формами гемобластозов и сотрудников института. Диагностику инфекции проводили с помощью ПЦР в реальном времени. У данного контингента также изучена динамика уровня антител класса IgG. Показано, что более высокий титр антител и более длительная их сохранность наблюдается у больных после тяжелой формы COVID-19 (с пневмонией). Различная динамика изменения уровня антител и высокая частота падения указывает на необходимость вакцинации и соблюдения строгих мер профилактики.

The COVID-19 was studied in 17 patients with various forms of hematological malingnancies and in 19 employees of the institute. Diagnostics of the infection were performed using real-time PCR. The dynamics of the level of IgG antibodies was also studied in this contingent. It has been shown that a higher antibody titer and their longer preservation are observed in patients after a severe form of COVID-19 (with pneumonia). Different dynamics of changes in the level of antibodies and a high drop frequency indicate the need for vaccination and compliance with strict preventive measures.

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The authors declare that there are no conflicts of interest present.